iSkincare

The science of skin boosters
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The Science of Skin Boosters: How Profhilo, Polynucleotides & Exosomes Work to Transform Your Skin

If you’ve been looking into advanced treatments to improve your skin’s texture, hydration, or overall health — but don’t want the volume or structure that comes with traditional dermal fillers — skin boosters could be the perfect solution. At iSkincare in Bournemouth, we specialise in cutting-edge regenerative treatments like Profhilo, Polynucleotides, and Exosomes, all of which restore the skin from the inside out.

These powerful treatments don’t mask the signs of ageing—they stimulate your body’s natural processes to rejuvenate your skin on a cellular level. In this blog, we break down how each of these boosters works, what makes them unique, and how they can be used to treat everything from fine lines to scarring and loss of elasticity.

What Are Skin Boosters?

Skin boosters are injectable or topical treatments designed to improve hydration, elasticity, collagen production, and skin texture. Unlike dermal fillers, they don’t add volume or change facial structure. Instead, they target the health and function of the skin itself—delivering bioactive substances like hyaluronic acid, nucleotides, or growth factors directly to the dermal layers.

At iSkincare, we offer three of the most scientifically advanced boosters available: Profhilo, Polynucleotides, and Exosomes. Each offers different benefits and mechanisms, and in some cases, can be combined for enhanced results.

Profhilo: Hydration + Collagen Activation in One

What it is:
Profhilo is an injectable treatment made from ultra-pure hyaluronic acid using patented NAHYCO® hybrid technology. Unlike traditional fillers, Profhilo spreads evenly under the skin like honey, without creating volume.

How it works:

It acts in two ways:

  1. Hydration: Instantly hydrates the skin by attracting and holding water.
  2. Biostimulation: Triggers the production of four types of collagen and elastin, improving firmness and elasticity over time.

Best for patients with:

  • Dull, dry, or crepey skin
  • Fine lines and mild laxity
  • Loss of firmness on the face, neck, décolletage, or hands

Treatment time: 3–4 sessions spaced 2–3 weeks apart
Visible results: 4–6 weeks after the second session

Polynucleotides: Cellular Regeneration and Healing

What they are:
Polynucleotides are fragments of purified DNA originally derived from salmon or trout (don’t worry—they’re processed and safe for human use). These tiny molecules act as biostimulators, encouraging cell renewal and tissue regeneration.

How they work:

  • Encourage the skin to regenerate with minimal inflammation
  • Deliver powerful anti-ageing signals to skin cells
  • Improve skin tone, texture, elasticity, and radiance

Best for patients with:

  • Uneven skin tone or rough texture
  • Enlarged pores or acne scarring
  • Early signs of ageing
  • Skin that needs a general reset and glow-up

Treatment time: 1–3 microneedling sessions with exosome infusion
Visible results: Within 2–4 weeks, with continued improvement over time

So, Which Skin Booster Is Right for You?

All three skin boostersProfhilo, Polynucleotides, and Exosomes—support the same goal: healthier, firmer, brighter skin. But each works a little differently.

TreatmentMain FunctionBest For
Profhilo Hydration +Collagen boostAgeing, fine lines, crepey skin
PolynucleotidesCellular repair + regenerationScarring, inflammation, sensitive skin
ExosomesStem-cell signalling +renewalTexture, dullness, acne scarring, pores

If you’re unsure which one is best for your skin goals, we’re here to help. At iSkincare, your journey starts with a thorough consultation. We use our clinical experience, skin assessments, and deep understanding of regenerative aesthetics to tailor your treatment plan—because no two skins are the same.

Start Your Skin Health Journey Today

Whether you’re in Bournemouth, Poole, or anywhere in Dorset, you can trust iSkincare to deliver results that are subtle, natural, and scientifically backed.

  • Experienced team of Registered Nurses: Rachael & Sofia
  • Safe, professional clinic with private off-road parking
  • Honest, evidence-based guidance with a warm, personal approach
  • Treatments rooted in regenerative medicine and long-term skin health

Your best skin is waiting. Let us help you find it.